The group sequential design has been well understood and widely applied in designs of late giantmouse tribeca phase clinical trial to enable potentially early stopping for efficacy or futility.The information fraction (IF) is one of the key elements to determine the decision boundary at the interim analyses.The family-wise error rate (FWER) control
Research regarding microbial fuel cells has been stimulated to reduce the operating costs and energy consumption of conventional wastewater treatment, and increase its profitability.However, these devices are challenging to study due to their complexity and sensitivity to both internal and external factors.Artificial intelligence (AI) has been used
Background and Objective: Pain is a shibori dot fabric common postoperative complaint, and the use of analgesics before surgical trauma can effectively prevent peripheral and central sensitization.We aimed to compare the preemptive effects of ibuprofen and celecoxib on post-operative pain after lower abdominal surgery in addicted patients.Materials
Shiga toxin-producing Escherichia coli (STEC) can cause diseases ranging from mild diarrhea to fatal extra-intestinal hemolytic uremic syndrome (HUS).Shiga toxin (Stx) is the key virulence factor in STEC, two Stx types (Stx1 and Stx2) and several subtypes varying in sequences, toxicity, and host specificity have been identified.Stx2l is a newly-des